PHANTASi Trial: Prehospital Antibiotics vs Sepsis

Background Antibiotics are one of the cornerstones of therapy in the treatment of sepsis/septic shock, however, according to the Surviving Sepsis Campaign (SSC) guidelines, time to antibiotics is a core […]

Which Route is Best for Epinephrine in OHCA?

Background Epinephrine remains a staple in cardiopulmonary resuscitation (CPR) in out-of-hospital cardiac arrest (OHCA).  However, the optimal dose, timing, and route of administration are still unknown.  Standard dosing of epinephrine […]

The Death of MONA in ACS: Oxygen

The Death of MONA in ACS: Oxygen by Salim R. Rezaie, MD   Background: The first report for supplemental oxygen for angina was in 1900, and since then oxygen therapy […]

In the Pipeline: Head Up CPR in OHCA?

Background: Head up (HUP) CPR is a new concept to me.  The theory behind HUP is it allows for venous blood to drain from the brain to the heart thereby […]